Sani Membranes A/S Hall 8 / C43

Centrifuge Killer

Replace your disk stack / high speed centrifuge

Vibro Membrane Filtration (VMF) enables continuous concentration of media using membrane filtration, thus offering an alternative to conventional centrifugal separation systems, such as disk stack centrifuges and high speed centrifuges.

VMF is ideal for pharmaceutical proteins, monoclonal antibodies (mAbs), insulin, starter cultures and probiotic products, extracellular and intracellular enzymes

VMF enables up to 96% API yield

SANI Membranes is proud to announce the introduction of the new, smaller version of the Vibro-I series, bridging the gap between benchtop filtration units and industrial units

The Vibro® technology has become the work horse for filtration, separation and concentration processes across many applications such as biopharma, algae, new green proteins and carbon nanomaterials. With the introduction of a smaller Vibro-I unit, 2.5m² unit, scaling your production capacity has become even simpler. Due to the unique technology of Vibro® Filtration, the process from benchtop filtration units is identical to that of larger units, meaning that the technology is ideal for scaling, as the user can expect the same results when going from one Vibro® unit to another, regardless of size.

Being founded in 2014, SANI Membranes is a relatively new player in the filtration industry but has quickly gained momentum with the Vibro® Technology, characterized by its low and uniform Trans Membrane Pressure, making it possible to achieve very high concentrations, eliminate shear and increase yield by up to 25%.

Truly Disruptive Micro- and Ultrafiltration Technology with Uniform TMP

SANI Membranes has developed a new and patented membrane filtration technology based on the Free Flow Plate modules and the Vibro technology. The Vibro technology delivers efficient continuous micro- and ultrafiltration with less fouling, less energy consumption and with a simple and sanitary design.

The Vibro technology is based on the crossflow filtration principle, but the cleansing turbulence at the membrane surface is here created by vibrating the membrane relative to the feed instead of applying a fast cross flow. The turbulence is only produced at the membrane surface and the huge pressure loss from a traditional cross flow is eliminated. Consequently, the transmembrane pressure (TMP) becomes close to uniform throughout the system - making unique process control and sharper separations possible.

The key features of the Vibro technology that will be explained are improved separation due to a uniform TMP obtained through fouling reducing turbulence achieved by moving the membrane relative to the media. The design opens for operation at very low TMP in the entire system (e.g. 0.10 bar) and this is the key to continuous fouling free microfiltration with high transmission of target molecules. Several test underlines that in many applications higher pressures reduce flux in microfiltration and always higher pressure seems to reduce transmission.

The open plate design supports operation with high concentration, viscosity and solid loads, and this combined with vibro technology leads to very high savings in pumping energy and cooling.

The technology is successfully implemented in continuous microfiltration of fermentation broths with exceptional transmission of target molecules even at high cell/cell-debris concentrations. The technology is also as a subsequent step implemented in UF concentration of proteins and other target molecules to remarkably high concentrations with extremely low shear on the media.

Innovative Free Flow Plate™ technology & the disruptive Vibro™ technology

SANI Membranes ApS is a Danish cleantech company producing innovative continuous Micro- and Ultrafiltration solution for the Biotech, Pharma, Food and Process industries.

Vibro-LE is the perfect benchtop filtration solution for process development and small-scale filtration applications. Low fouling continuous filtration where the filter is kept clean by vibration shear.

Vibro-I is our industrial MF and UF solution. The Vibro-I is perfect for difficult MF applications where high transmission is crucial and can concentrate your valuable products to extreme concentrations in UF.

The patented Vibro technology creates the needed turbulence on all membrane surfaces by vibrating the membrane relative to the media. The Vibro technology eliminates the need for a cross flow pump and delivers uniform TMP throughout the system at exceptional low energy consumption.

• Ideal Separation
• Unique Microfiltration
• Low Energy Consumption
• High Concentration, Viscosity and Solids Load
• Better Product Quality
• Higher Yield
• Sanitary