Currently, expanded polytetrafluoroethylene (ePTFE) is the most widely used high performance filtration material as a microporous membrane in air and liquid filtration due to its strong nano size filaments, extreme chemical resistance, high temperature up to 260 °C, low friction coefficient, very fine pore control, hydro/oleophobic, and high permeability.

ePTFE seems to be the best filtration material in air and liquid filtration applications. However, ePTFE is a PFAS even though it is high molecular weight polytetrafluoroethylene and insoluble in water.

Current and future PFAS regulations on ePTFE in US, Europe and Asia will be extensively discussed. Alternate PFAS free materials in air and liquid filtration for next 30 years will be proposed and compared with ePTFE.