Among the broad class of per- and polyfluoroalkyl substances (PFAS), short- and ultra-short-chain compounds pose a distinct challenge for water treatment operators. Their small size, high mobility, and resistance to conventional treatments create a growing compliance challenge as regulations expand beyond legacy compounds such as PFOA and PFOS. Oxyle will present a modular treatment approach that combines targeted concentration technologies such as nanofiltration or foam fractionation with PFAS destruction via advanced photochemical reduction to permanently degrade and defluorinate these hard-to-treat substances. Results demonstrate effective elimination, including ~98% TFA degradation in industrial wastewater and ~99% PFBA degradation in contaminated groundwater. The session will highlight how this modular approach can overcome current treatment limitations and reduce operational and environmental risk.