Membrane filtration in BioProcessing has been a staple for many unit operations in both upstream and downstream applications. New technology using nanofibers has shown to increase flux by up to a factor of three, while maintaining equivalent high efficiency, providing a faster, more reliable and cost-effective alternative to traditional membrane filters.

This talk will provide a direct comparison between membrane filters and nanofiber composites using traditional BioProcessing streams for prefiltration applications. Certain advantages, such as 2-3 times the flux and 1.5-2 times the loading with similar capacity, will be discussed. Finally, the cost benefits of enhanced performance and higher pore size selectivity will be presented.